Endocrine Abstracts

Introduction: Thyroid carcinoma (TC) is the most common endocrine malignancy. Although the overall prognosis for patients with TC is good, up to 20% of patients develop recurrent or persistent disease after conventional therapy by total thyroidectomy and radioactive iodine (RAI). Amiodarone is a highly efficient anti-arrhythmic drug with a very long half-life, so it may interfere with RAI many months after the drug withdrawal. This case report mirrors the challenges of thyroid...

Introduction: Papillary thyroid carcinoma (PTC) is a differentiated thyroid carcinoma accounting for approximately 80% of all thyroid malignancies; in contrast only 1–2% of thyroid cancers are anaplastic. While the transformation of papillary thyroid carcinoma to the more aggressive anaplastic carcinoma represents a well known occurrence, the transformation of metastatic PTC in a distant location is an uncommon finding, but new insights from the BRAF(V600E) mutat...

Introduction: Struma ovarii is a rare condition which elicited considerable interest because of its many unique features like its relationship to teratoma and differentiated thyroid cancer. The most common thyroid carcinomas to arise in struma ovarii are papillary and follicular.Objectives: We describe two patients with differentiated thyroid carcinoma originating from malignant struma ovarii.Results: Our index patient is a 32-year...

Papillary thyroid carcinoma is a slow growing tumor and is reputed to have an excellent prognosis. In 10–20% of cases, the presence of lymph node metastases led to diagnosis.Objective: To present a patient with enlarged lateral cervical masses, present for 10 years, that proved to be lymph nodes with metastatic thyroid papillary carcinoma.Case report: We report a case of an 26-year-old female patient with 10 years evolution of...

There are still many questions remaining about the etiopathogenesis of thyroid cancer, themost common type of endocrine neoplasia. Numerous occupational and environmental exposureshave been shown to represent important risk factors that increase its incidence. Updated informationabout thyroid cancer diagnostics related to occupational and environmental risk factors is reviewedhere, considering an integrated risk assessment approach; new data concerning thyroid canceretiology a...

A rare ovarian teratoma consisting mainly of thyroid tissue, Struma ovarii accounts for up to 3% of all ovarian tumors. The thyroid tissue may demonstrate the same spectrum of pathological features as in the normal thyroid including benign and malignant changes.A 46-year-old woman was referred to our clinic in July 2015 by the oncologist, with the diagnosis of struma ovarii with carcinomatous transformation (follicular variant of papillary carcinoma).</p...